Cushing's syndrome is caused by prolonged exposure to adrenal gland-produced cortisol. The control of metabolism and fat accumulation depend on cortisol.
Chronically high cortisol levels can cause abdominal fat. Why Cushing's syndrome matters for abdominal fat:
Cushing's syndrome's elevated cortisol levels can cause abdominal fat buildup. Central obesity, which causes a "buffalo hump" on the upper back and a rounded, bulging abdomen, generally occurs from fat redistribution.
Chronically elevated cortisol levels can cause insulin resistance. Insulin resistance raises blood sugar and stores extra glucose as fat, especially in the abdomen.
Cortisol affects appetite and diet. Cushing's syndrome can increase appetite, desires for high-calorie foods, and carbohydrate preference. Changes in diet can cause weight gain, particularly belly fat.
Cushing's syndrome can cause water retention and swelling, resulting in a rounded abdomen. This is commonly linked to abdominal fat.
Cushing's syndrome symptoms include fast weight gain, central obesity, muscle weakness, and skin abnormalities. Patients should seek medical attention for diagnosis.
Cushing's syndrome affects cortisol levels, which can shift fat distribution, insulin resistance, and metabolic abnormalities, contributing to increased belly fat.
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